3d0e

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(New page: '''Unreleased structure''' The entry 3d0e is ON HOLD until Paper Publication Authors: Concha, N.O., Smallwood, A. Description: Crystal structure of human Akt2 in complex with GSK690693...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3d0e.jpg|left|200px]]
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The entry 3d0e is ON HOLD until Paper Publication
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{{STRUCTURE_3d0e| PDB=3d0e | SCENE= }}
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Authors: Concha, N.O., Smallwood, A.
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===Crystal structure of human Akt2 in complex with GSK690693===
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Description: Crystal structure of human Akt2 in complex with GSK690693
 
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{{ABSTRACT_PUBMED_18800763}}
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:35:46 2008''
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==Disease==
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Known disease associated with this structure: Diabetes mellitus, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164731 164731]]
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==About this Structure==
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3D0E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0E OCA].
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==Reference==
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Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]o xy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase., Heerding DA, Rhodes N, Leber JD, Clark TJ, Keenan RM, Lafrance LV, Li M, Safonov IG, Takata DT, Venslavsky JW, Yamashita DS, Choudhry AE, Copeland RA, Lai Z, Schaber MD, Tummino PJ, Strum SL, Wood ER, Duckett DR, Eberwein D, Knick VB, Lansing TJ, McConnell RT, Zhang S, Minthorn EA, Concha NO, Warren GL, Kumar R, J Med Chem. 2008 Sep 25;51(18):5663-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18800763 18800763]
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
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[[Category: Concha, N O.]]
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[[Category: Smallwood, A.]]
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[[Category: Akt2]]
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[[Category: Atp-binding]]
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[[Category: Human]]
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[[Category: Inhibitor]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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[[Category: Transferase inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 22 10:44:37 2008''

Revision as of 08:44, 22 October 2008

Image:3d0e.jpg

Template:STRUCTURE 3d0e

Contents

Crystal structure of human Akt2 in complex with GSK690693

Template:ABSTRACT PUBMED 18800763

Disease

Known disease associated with this structure: Diabetes mellitus, type II OMIM:[164731]

About this Structure

3D0E is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]o xy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase., Heerding DA, Rhodes N, Leber JD, Clark TJ, Keenan RM, Lafrance LV, Li M, Safonov IG, Takata DT, Venslavsky JW, Yamashita DS, Choudhry AE, Copeland RA, Lai Z, Schaber MD, Tummino PJ, Strum SL, Wood ER, Duckett DR, Eberwein D, Knick VB, Lansing TJ, McConnell RT, Zhang S, Minthorn EA, Concha NO, Warren GL, Kumar R, J Med Chem. 2008 Sep 25;51(18):5663-79. PMID:18800763

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