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Template:STRUCTURE 1b41

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Revision as of 20:27, 16 February 2009

1b41, resolution 2.76Å ()

Ligands:

Non-Standard Residues:

Gene:

ACHE (Homo sapiens)

Activity:

Acetylcholinesterase, with EC number 3.1.1.7

Domains:

Esterase_lipase, COesterase, snake_toxin

Structural annotation:
Resources:	CATH : 1B41A00, 1B41B00 InterPro : Ipr014788, Ipr000997, Ipr002018 Pfam : PF00135 SCOP : d1b41a_, d1b41b_ UniProt : P22303, P0C1Z0

Functional annotation:
Cellular component:	extracellular region membrane basal lamina cell junction synapse Golgi apparatus perinuclear region of cytoplasm
Biological process:	cell proliferation osteoblast development response to wounding DNA replication cell adhesion amyloid precursor protein metabolic process acetylcholine catabolic process in synaptic cleft positive regulation of protein secretion acetylcholine catabolic process synaptogenesis negative regulation of synaptic transmission, cholinergic neurotransmitter catabolic process nervous system development muscle development
Molecular function:	protein homodimerization activity collagen binding hydrolase activity acetylcholinesterase activity serine hydrolase activity acetylcholine binding cholinesterase activity beta-amyloid binding laminin-1 binding

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Explanation,
Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1b41"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1b41, resolution 2.76&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1b41]], resolution 2.76&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |LIGAND= <scene name='pdbligand=NDG:SUGAR+(N-ACETYL-D-GLUCOSAMINE)'>NDG</scene>
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span>
@@ Line 11: / Line 11: @@
 |COMPONENT={{GO|id=GO:0005576 | text = extracellular region}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0005605 | text = basal lamina}}{{GO|id=GO:0030054 | text = cell junction}}{{GO|id=GO:0045202 | text = synapse}}{{GO|id=GO:0005794 | text = Golgi apparatus}}{{GO|id=GO:0048471 | text = perinuclear region of cytoplasm}}
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1b41A00 1B41A00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1b41B00 1B41B00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014788 Ipr014788], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000997 Ipr000997], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002018 Ipr002018]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00135 PF00135]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34621 d1b41a_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=44409 d1b41b_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P22303 P22303], [http://ca.expasy.org/cgi-bin/niceprot.pl?P0C1Z0 P0C1Z0]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=ACHE ACHE]</span>
+|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_1b41_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>B [x]</text>
+<name>jmb_1b41_B</name>
+<title>toggle chain B</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 1b41

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Revision as of 20:27, 16 February 2009

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