1lnh
From Proteopedia
(New page: 200px<br /> <applet load="1lnh" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lnh, resolution 2.6Å" /> '''LIPOXYGENASE-3(SOYBE...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1LNH is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Glycine_max Glycine max]] with FE2 as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1LNH OCA]]. | + | 1LNH is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Glycine_max Glycine max]] with FE2 as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: FE. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1LNH OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:41:46 2007'' |
Revision as of 10:37, 30 October 2007
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LIPOXYGENASE-3(SOYBEAN) NON-HEME FE(II) METALLOPROTEIN
Overview
Soybean lipoxygenase isoenzyme L3 represents a second example (after L1), of the X-ray structure (R = 17% at 2.6 A resolution) for a member of the, large family of lipoxygenases. L1 and L3 have different characteristics in, catalysis, although they share 72% sequence identity (the changes impact, 255 amino acids) and similar folding (average C alpha rms deviation of 1, A). The critical nonheme iron site has the same features as for L1:3O and, 3N in pseudo C3v orientation, with two oxygen atoms (from Asn713 and, water) at a nonbinding distance. Asn713 and His518 are strategically, located at the junction of three cavities connecting the iron site with, the molecule surface. The most visible differences between L1 and L3, isoenzymes occur in and near these cavities, affecting their ... [(full description)]
About this Structure
1LNH is a [Single protein] structure of sequence from [Glycine max] with FE2 as [ligand]. Structure known Active Site: FE. Full crystallographic information is available from [OCA].
Reference
Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme., Skrzypczak-Jankun E, Amzel LM, Kroa BA, Funk MO Jr, Proteins. 1997 Sep;29(1):15-31. PMID:9294864
Page seeded by OCA on Tue Oct 30 12:41:46 2007
