1boz
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 1BOZ is a | + | 1BOZ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BOZ OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:9719595</ref><references group="xtra"/> | |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Single protein]] | ||
[[Category: Cody, V.]] | [[Category: Cody, V.]] | ||
[[Category: Galitsky, N.]] | [[Category: Galitsky, N.]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:43:47 2009'' |
Revision as of 07:43, 17 February 2009
STRUCTURE-BASED DESIGN AND SYNTHESIS OF LIPOPHILIC 2,4-DIAMINO-6-SUBSTITUTED QUINAZOLINES AND THEIR EVALUATION AS INHIBITORS OF DIHYDROFOLATE REDUCTASE AND POTENTIAL ANTITUMOR AGENTS
Template:ABSTRACT PUBMED 9719595
About this Structure
1BOZ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gangjee A, Vidwans AP, Vasudevan A, Queener SF, Kisliuk RL, Cody V, Li R, Galitsky N, Luft JR, Pangborn W. Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents. J Med Chem. 1998 Aug 27;41(18):3426-34. PMID:9719595 doi:10.1021/jm980081y
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