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1ej6
From Proteopedia
(New page: 200px<br /><applet load="1ej6" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ej6, resolution 3.6Å" /> '''Reovirus core'''<br /...) |
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| - | [[Image:1ej6.gif|left|200px]]<br /><applet load="1ej6" size=" | + | [[Image:1ej6.gif|left|200px]]<br /><applet load="1ej6" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1ej6, resolution 3.6Å" /> | caption="1ej6, resolution 3.6Å" /> | ||
'''Reovirus core'''<br /> | '''Reovirus core'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The reovirus core is an assembly with a relative molecular mass of 52 | + | The reovirus core is an assembly with a relative molecular mass of 52 million that synthesizes, modifies and exports viral messenger RNA. Analysis of its structure by X-ray crystallography shows that there are alternative, specific and completely non-equivalent contacts made by several surfaces of two of its proteins; that the RNA capping and export apparatus is a hollow cylinder, which probably sequesters its substrate to ensure completion of the capping reactions; that the genomic double-stranded RNA is coiled into concentric layers within the particle; and that there is a protein shell that appears to be common to all groups of double-stranded RNA viruses. |
==About this Structure== | ==About this Structure== | ||
| - | 1EJ6 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Reovirus_sp. Reovirus sp.] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1EJ6 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Reovirus_sp. Reovirus sp.] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJ6 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Reovirus sp.]] | [[Category: Reovirus sp.]] | ||
| - | [[Category: Harrison, S | + | [[Category: Harrison, S C.]] |
| - | [[Category: Nibert, M | + | [[Category: Nibert, M L.]] |
| - | [[Category: Reinisch, K | + | [[Category: Reinisch, K M.]] |
[[Category: ZN]] | [[Category: ZN]] | ||
[[Category: dsrna virus]] | [[Category: dsrna virus]] | ||
| Line 27: | Line 27: | ||
[[Category: zinc finger]] | [[Category: zinc finger]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:28:19 2008'' |
Revision as of 10:28, 21 February 2008
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Reovirus core
Overview
The reovirus core is an assembly with a relative molecular mass of 52 million that synthesizes, modifies and exports viral messenger RNA. Analysis of its structure by X-ray crystallography shows that there are alternative, specific and completely non-equivalent contacts made by several surfaces of two of its proteins; that the RNA capping and export apparatus is a hollow cylinder, which probably sequesters its substrate to ensure completion of the capping reactions; that the genomic double-stranded RNA is coiled into concentric layers within the particle; and that there is a protein shell that appears to be common to all groups of double-stranded RNA viruses.
About this Structure
1EJ6 is a Protein complex structure of sequences from Reovirus sp. with as ligand. Full crystallographic information is available from OCA.
Reference
Structure of the reovirus core at 3.6 A resolution., Reinisch KM, Nibert ML, Harrison SC, Nature. 2000 Apr 27;404(6781):960-7. PMID:10801118
Page seeded by OCA on Thu Feb 21 12:28:19 2008
