1e26

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==About this Structure==
==About this Structure==
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1E26 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].
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1E26 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E26 OCA].
==Reference==
==Reference==
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Design, synthesis, and X-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent., Gangjee A, Yu J, McGuire JJ, Cody V, Galitsky N, Kisliuk RL, Queener SF, J Med Chem. 2000 Oct 19;43(21):3837-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11052789 11052789]
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<ref group="xtra">PMID:11052789</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Pneumocystis carinii]]
[[Category: Pneumocystis carinii]]
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[[Category: Single protein]]
 
[[Category: Cody, V.]]
[[Category: Cody, V.]]
[[Category: Galitsky, N.]]
[[Category: Galitsky, N.]]
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[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:01:29 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:08:56 2009''

Revision as of 12:08, 17 February 2009

Template:STRUCTURE 1e26

DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.

Template:ABSTRACT PUBMED 11052789

About this Structure

1E26 is a 1 chain structure of sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.

Reference

  • Gangjee A, Yu J, McGuire JJ, Cody V, Galitsky N, Kisliuk RL, Queener SF. Design, synthesis, and X-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent. J Med Chem. 2000 Oct 19;43(21):3837-51. PMID:11052789

Page seeded by OCA on Tue Feb 17 14:08:56 2009

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