1f8v
From Proteopedia
(New page: 200px<br /><applet load="1f8v" size="450" color="white" frame="true" align="right" spinBox="true" caption="1f8v, resolution 3.00Å" /> '''THE STRUCTURE OF PAR...) |
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| - | [[Image:1f8v.gif|left|200px]]<br /><applet load="1f8v" size=" | + | [[Image:1f8v.gif|left|200px]]<br /><applet load="1f8v" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1f8v, resolution 3.00Å" /> | caption="1f8v, resolution 3.00Å" /> | ||
'''THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA'''<br /> | '''THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The 3.0 A resolution crystal structure of Pariacoto virus (PaV) reveals | + | The 3.0 A resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid. Under the protein shell of the T = 3 quasi equivalent capsid lies a dodecahedral cage composed of RNA duplex that accounts for approximately 35% of the single-stranded RNA genome. The highly basic N-terminal regions (residues 7-54) of the subunits, forming pentamers (A subunits) are clearly visible in the density map and make numerous interactions with the RNA cage. The C-terminal segments (residues 394-401) of the A subunits lie in channels near the quasi three-fold axes. Electron cryo-microscopy and image reconstruction of PaV particles clearly show the dodecahedral RNA cage. |
==About this Structure== | ==About this Structure== | ||
| - | 1F8V is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Pariacato_virus Pariacato virus] with SO4 and CA as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 1F8V is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Pariacato_virus Pariacato virus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F8V OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Pariacato virus]] | [[Category: Pariacato virus]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| - | [[Category: Ball, L | + | [[Category: Ball, L A.]] |
| - | [[Category: Johnson, J | + | [[Category: Johnson, J E.]] |
| - | [[Category: Johnson, K | + | [[Category: Johnson, K N.]] |
[[Category: Lin, T.]] | [[Category: Lin, T.]] | ||
[[Category: Tang, L.]] | [[Category: Tang, L.]] | ||
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[[Category: rna duplex]] | [[Category: rna duplex]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:36:08 2008'' |
Revision as of 10:36, 21 February 2008
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THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA
Overview
The 3.0 A resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid. Under the protein shell of the T = 3 quasi equivalent capsid lies a dodecahedral cage composed of RNA duplex that accounts for approximately 35% of the single-stranded RNA genome. The highly basic N-terminal regions (residues 7-54) of the subunits, forming pentamers (A subunits) are clearly visible in the density map and make numerous interactions with the RNA cage. The C-terminal segments (residues 394-401) of the A subunits lie in channels near the quasi three-fold axes. Electron cryo-microscopy and image reconstruction of PaV particles clearly show the dodecahedral RNA cage.
About this Structure
1F8V is a Protein complex structure of sequences from Pariacato virus with and as ligands. Full crystallographic information is available from OCA.
Reference
The structure of pariacoto virus reveals a dodecahedral cage of duplex RNA., Tang L, Johnson KN, Ball LA, Lin T, Yeager M, Johnson JE, Nat Struct Biol. 2001 Jan;8(1):77-83. PMID:11135676
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