1g0w
From Proteopedia
(New page: 200px<br /><applet load="1g0w" size="450" color="white" frame="true" align="right" spinBox="true" caption="1g0w, resolution 2.30Å" /> '''CRYSTAL STRUCTURE OF...) |
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| - | [[Image:1g0w.jpg|left|200px]]<br /><applet load="1g0w" size=" | + | [[Image:1g0w.jpg|left|200px]]<br /><applet load="1g0w" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1g0w, resolution 2.30Å" /> | caption="1g0w, resolution 2.30Å" /> | ||
'''CRYSTAL STRUCTURE OF BOVINE RETINAL CREATINE KINASE'''<br /> | '''CRYSTAL STRUCTURE OF BOVINE RETINAL CREATINE KINASE'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Creatine kinase (CK) catalyses the reversible transfer of the phosphate | + | Creatine kinase (CK) catalyses the reversible transfer of the phosphate moiety from phosphocreatine (PCr) to ADP, generating creatine and ATP. The crystal structure of a cytosolic brain-type creatine kinase is reported at 2.3 A. The biological dimer sits on a crystallographic twofold axis. The N-terminal residues of both subunits come very close to the crystallographic twofold at the dimer interface. The electron density observed is consistent with two alternative conformations for the N-termini, as previously found for chicken brain-type creatine kinase. |
==About this Structure== | ==About this Structure== | ||
| - | 1G0W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Creatine_kinase Creatine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.2 2.7.3.2] Full crystallographic information is available from [http:// | + | 1G0W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Creatine_kinase Creatine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.2 2.7.3.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G0W OCA]. |
==Reference== | ==Reference== | ||
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[[Category: guanidino kinase cellular energy metabolism]] | [[Category: guanidino kinase cellular energy metabolism]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:44:53 2008'' |
Revision as of 10:44, 21 February 2008
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CRYSTAL STRUCTURE OF BOVINE RETINAL CREATINE KINASE
Overview
Creatine kinase (CK) catalyses the reversible transfer of the phosphate moiety from phosphocreatine (PCr) to ADP, generating creatine and ATP. The crystal structure of a cytosolic brain-type creatine kinase is reported at 2.3 A. The biological dimer sits on a crystallographic twofold axis. The N-terminal residues of both subunits come very close to the crystallographic twofold at the dimer interface. The electron density observed is consistent with two alternative conformations for the N-termini, as previously found for chicken brain-type creatine kinase.
About this Structure
1G0W is a Single protein structure of sequence from Bos taurus with as ligand. Active as Creatine kinase, with EC number 2.7.3.2 Full crystallographic information is available from OCA.
Reference
The three-dimensional structure of cytosolic bovine retinal creatine kinase., Tisi D, Bax B, Loew A, Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):187-93. PMID:11173463
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