1h6v

From Proteopedia

(Difference between revisions)

Revision as of 14:24, 17 February 2009

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

Image:1h6v.png

1h6v, resolution 3.00Å ()

Ligands:

Non-Standard Residues:

Activity:

Thioredoxin-disulfide reductase, with EC number 1.8.1.9

Structural annotation:

Resources:

CATH : 1H6Va03, 1H6Va01, 1H6Va02, 1H6Vb03, 1H6Vb01, 1H6Vb02, 1H6Vc01, 1H6Vc02, 1H6Vc03, 1H6Vd01, 1H6Vd02, 1H6Vd03, 1H6Ve01, 1H6Ve02, 1H6Ve03, 1H6Vf01, 1H6Vf02, 1H6Vf03
InterPro : Ipr004099, Ipr012999, Ipr001100, Ipr006338, Ipr013027, Ipr001327, Ipr000815
Pfam : PF02852, PF00070, PF07992
SCOP : d1h6va1, d1h6va3, d1h6va2, d1h6vb1, d1h6vb2, d1h6vb3, d1h6vc3, d1h6vc1, d1h6vc2, d1h6vd1, d1h6vd2, d1h6vd3, d1h6ve1, d1h6ve3, d1h6ve2, d1h6vf1, d1h6vf3, d1h6vf2
UniProt : O89049

Functional annotation:
Cellular component:	cytosol cytoplasm
Biological process:	cell proliferation electron transport response to oxidative stress hydrogen peroxide catabolic process cell redox homeostasis thioredoxin pathway
Molecular function:	NADP binding FAD binding thioredoxin-disulfide reductase activity oxidoreductase activity selenium binding oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

MAMMALIAN THIOREDOXIN REDUCTASE

Template:ABSTRACT PUBMED 11481439

About this Structure

1H6V is a 6 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Sandalova T, Zhong L, Lindqvist Y, Holmgren A, Schneider G. Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9533-8. Epub 2001 Jul 31. PMID:11481439 doi:10.1073/pnas.171178698

Page seeded by OCA on Tue Feb 17 16:24:56 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h6v"

@@ Line 20: / Line 20: @@
 ==About this Structure==
-H6V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H6V OCA].
+H6V is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H6V OCA].
 ==Reference==
-Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme., Sandalova T, Zhong L, Lindqvist Y, Holmgren A, Schneider G, Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9533-8. Epub 2001 Jul 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11481439 11481439]
+<ref group="xtra">PMID:11481439</ref><references group="xtra"/>
 [[Category: Rattus norvegicus]]
-[[Category: Single protein]]
 [[Category: Thioredoxin-disulfide reductase]]
 [[Category: Holmgren, A.]]
@@ Line 35: / Line 34: @@
 [[Category: Pyridine nucleotide-disulfide oxidoreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 06:43:20 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:24:56 2009''

1h6v

From Proteopedia

Revision as of 14:24, 17 February 2009

MAMMALIAN THIOREDOXIN REDUCTASE

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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