1iiq

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==About this Structure==
==About this Structure==
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1IIQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_-_1 Human immunodeficiency virus - 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IIQ OCA].
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1IIQ is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_-_1 Human immunodeficiency virus - 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IIQ OCA].
==Reference==
==Reference==
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Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor., Dohnalek J, Hasek J, Duskova J, Petrokova H, Hradilek M, Soucek M, Konvalinka J, Brynda J, Sedlacek J, Fabry M, J Med Chem. 2002 Mar 28;45(7):1432-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11906284 11906284]
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<ref group="xtra">PMID:11906284</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus - 1]]
[[Category: Human immunodeficiency virus - 1]]
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[[Category: Single protein]]
 
[[Category: Brynda, J.]]
[[Category: Brynda, J.]]
[[Category: Dohnalek, J.]]
[[Category: Dohnalek, J.]]
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[[Category: Protease]]
[[Category: Protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 12:17:17 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:57:22 2009''

Revision as of 10:57, 17 February 2009

Template:STRUCTURE 1iiq

CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR

Template:ABSTRACT PUBMED 11906284

About this Structure

1IIQ is a 3 chains structure of sequences from Human immunodeficiency virus - 1. Full crystallographic information is available from OCA.

Reference

  • Dohnalek J, Hasek J, Duskova J, Petrokova H, Hradilek M, Soucek M, Konvalinka J, Brynda J, Sedlacek J, Fabry M. Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor. J Med Chem. 2002 Mar 28;45(7):1432-8. PMID:11906284

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