1ijn

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==Disease==
==Disease==
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Known disease associated with this structure: Amyloid neuropathy, familial, several allelic types OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176300 176300]], Amyloidosis, senile systemic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176300 176300]], Carpal tunnel syndrome, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176300 176300]], Dystransthyretinemic hyperthyroxinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176300 176300]]
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Known disease associated with this structure: Amyloid polyneuropathy, several types OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176300 176300]], Amyloidosis, senile systemic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176300 176300]], Carpal tunnel syndrome, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176300 176300]], Dystransthyretinemic hyperthyroxinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176300 176300]]
==About this Structure==
==About this Structure==
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1IJN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IJN OCA].
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1IJN is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IJN OCA].
==Reference==
==Reference==
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Cys114-linked dimers of transthyretin are compatible with amyloid formation., Karlsson A, Olofsson A, Eneqvist T, Sauer-Eriksson AE, Biochemistry. 2005 Oct 4;44(39):13063-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16185074 16185074]
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<ref group="xtra">PMID:16185074</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Eneqvist, T.]]
[[Category: Eneqvist, T.]]
[[Category: Karlsson, A.]]
[[Category: Karlsson, A.]]
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[[Category: Greek key]]
[[Category: Greek key]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 12:22:04 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:44:35 2009''

Revision as of 01:44, 18 February 2009

Image:1ijn.png

Template:STRUCTURE 1ijn

Contents

Crystal structure of the transthyretin mutant TTR C10A/Y114C

Template:ABSTRACT PUBMED 16185074

Disease

Known disease associated with this structure: Amyloid polyneuropathy, several types OMIM:[176300], Amyloidosis, senile systemic OMIM:[176300], Carpal tunnel syndrome, familial OMIM:[176300], Dystransthyretinemic hyperthyroxinemia OMIM:[176300]

About this Structure

1IJN is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Karlsson A, Olofsson A, Eneqvist T, Sauer-Eriksson AE. Cys114-linked dimers of transthyretin are compatible with amyloid formation. Biochemistry. 2005 Oct 4;44(39):13063-70. PMID:16185074 doi:10.1021/bi050795s

Page seeded by OCA on Wed Feb 18 03:44:35 2009

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