1izh

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==About this Structure==
==About this Structure==
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1IZH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IZH OCA].
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1IZH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IZH OCA].
==Reference==
==Reference==
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Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains., Weber J, Mesters JR, Lepsik M, Prejdova J, Svec M, Sponarova J, Mlcochova P, Skalicka K, Strisovsky K, Uhlikova T, Soucek M, Machala L, Stankova M, Vondrasek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J, J Mol Biol. 2002 Dec 6;324(4):739-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12460574 12460574]
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<ref group="xtra">PMID:12460574</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Single protein]]
 
[[Category: Hilgenfeld, R.]]
[[Category: Hilgenfeld, R.]]
[[Category: Klimkait, T.]]
[[Category: Klimkait, T.]]
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[[Category: Subsite binding]]
[[Category: Subsite binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 14:16:08 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:25:22 2009''

Revision as of 02:25, 17 February 2009

Image:1izh.png

Template:STRUCTURE 1izh

Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants

Template:ABSTRACT PUBMED 12460574

About this Structure

1IZH is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Weber J, Mesters JR, Lepsik M, Prejdova J, Svec M, Sponarova J, Mlcochova P, Skalicka K, Strisovsky K, Uhlikova T, Soucek M, Machala L, Stankova M, Vondrasek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J. Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains. J Mol Biol. 2002 Dec 6;324(4):739-54. PMID:12460574

Page seeded by OCA on Tue Feb 17 04:25:22 2009

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