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1jr4
From Proteopedia
(Difference between revisions)
| Line 14: | Line 14: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1JR4 is a | + | 1JR4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JR4 OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:12404486</ref><references group="xtra"/> | |
[[Category: Catechol O-methyltransferase]] | [[Category: Catechol O-methyltransferase]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Ruf, A.]] | [[Category: Ruf, A.]] | ||
[[Category: Stihle, M.]] | [[Category: Stihle, M.]] | ||
| Line 28: | Line 27: | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:34:19 2009'' |
Revision as of 14:34, 17 February 2009
CATECHOL O-METHYLTRANSFERASE BISUBSTRATE-INHIBITOR COMPLEX
About this Structure
1JR4 is a 1 chain structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Lerner C, Ruf A, Gramlich V, Masjost B, Zurcher G, Jakob-Roetne R, Borroni E, Diederich F. X-ray Crystal Structure of a Bisubstrate Inhibitor Bound to the Enzyme Catechol-O-methyltransferase: A Dramatic Effect of Inhibitor Preorganization on Binding Affinity We thank F. Hoffmann-La Roche for generous support of this work. We are grateful to P. Malherbe for the cloning of COMT, P. Caspers for the expression of COMT, A. Cesura for enzyme purification, B. Wipf for fermentation, and H. W. Lahm for sequencing. Angew Chem Int Ed Engl. 2001 Nov 5;40(21):4040-4042. PMID:12404486
Page seeded by OCA on Tue Feb 17 16:34:19 2009
