1kw0

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==Disease==
==Disease==
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Known disease associated with this structure: Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]], Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]]
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Known disease associated with this structure: Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]], Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612349 612349]]
==About this Structure==
==About this Structure==
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1KW0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KW0 OCA].
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1KW0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KW0 OCA].
==Reference==
==Reference==
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Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation., Andersen OA, Flatmark T, Hough E, J Mol Biol. 2002 Jul 26;320(5):1095-108. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12126628 12126628]
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<ref group="xtra">PMID:12126628</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylalanine 4-monooxygenase]]
[[Category: Phenylalanine 4-monooxygenase]]
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[[Category: Single protein]]
 
[[Category: Andersen, O A.]]
[[Category: Andersen, O A.]]
[[Category: Flatmark, T.]]
[[Category: Flatmark, T.]]
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[[Category: Ferrous iron]]
[[Category: Ferrous iron]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 11:07:33 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:53:10 2009''

Revision as of 05:53, 17 February 2009

Template:STRUCTURE 1kw0

Contents

Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine

Template:ABSTRACT PUBMED 12126628

Disease

Known disease associated with this structure: Phenylketonuria OMIM:[612349], Hyperphenylalaninemia, mild OMIM:[612349]

About this Structure

1KW0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Andersen OA, Flatmark T, Hough E. Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation. J Mol Biol. 2002 Jul 26;320(5):1095-108. PMID:12126628

Page seeded by OCA on Tue Feb 17 07:53:10 2009

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