SelB
From Proteopedia
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{{STRUCTURE_1wsu | PDB=1wsu | SCENE=Goodsell_Sandbox/1wsu-recognition0/1 }} | {{STRUCTURE_1wsu | PDB=1wsu | SCENE=Goodsell_Sandbox/1wsu-recognition0/1 }} | ||
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Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms | Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms | ||
<scene name='SelB_Recognition/1wsu-recognition1/3'>specific hydrogen bonds with the protein and with two bridging water molecules (shown in cyan in the jmol).</scene> | <scene name='SelB_Recognition/1wsu-recognition1/3'>specific hydrogen bonds with the protein and with two bridging water molecules (shown in cyan in the jmol).</scene> | ||
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In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of | In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of | ||
<scene name='Sandbox_14/1wsu-recognition5/1'>arginine 606.</scene> | <scene name='Sandbox_14/1wsu-recognition5/1'>arginine 606.</scene> | ||
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Revision as of 16:59, 22 July 2008
Template:STRUCTURE 1wsu Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms The planar base is also sandwiched between in the protein, which form a tight hydrophobic pocket. This is best seen using a The overall shape of the hairpin is recognized by contacts with several In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Eran Hodis, David S. Goodsell, Joel L. Sussman, David Canner, Eric Martz, Alexander Berchansky
