2p8k

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==About this Structure==
==About this Structure==
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2P8K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8K OCA].
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2P8K is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8K OCA].
==Reference==
==Reference==
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Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development., Cavazzuti A, Paglietti G, Hunter WN, Gamarro F, Piras S, Loriga M, Allecca S, Corona P, McLuskey K, Tulloch L, Gibellini F, Ferrari S, Costi MP, Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1448-53. Epub 2008 Feb 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18245389 18245389]
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<ref group="xtra">PMID:18245389</ref><references group="xtra"/>
[[Category: Leishmania major]]
[[Category: Leishmania major]]
[[Category: Pteridine reductase]]
[[Category: Pteridine reductase]]
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[[Category: Single protein]]
 
[[Category: Gibellini, F.]]
[[Category: Gibellini, F.]]
[[Category: Hunter, W N.]]
[[Category: Hunter, W N.]]
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[[Category: Trypanosoma]]
[[Category: Trypanosoma]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 10:11:57 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:24:22 2009''

Revision as of 10:24, 16 February 2009

Template:STRUCTURE 2p8k

Selective screening and design to identify inhibitors of Leishmania major pteridine reductase 1.

Template:ABSTRACT PUBMED 18245389

About this Structure

2P8K is a 8 chains structure of sequences from Leishmania major. Full crystallographic information is available from OCA.

Reference

  • Cavazzuti A, Paglietti G, Hunter WN, Gamarro F, Piras S, Loriga M, Allecca S, Corona P, McLuskey K, Tulloch L, Gibellini F, Ferrari S, Costi MP. Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1448-53. Epub 2008 Feb 1. PMID:18245389

Page seeded by OCA on Mon Feb 16 12:24:22 2009

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