1opl

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==About this Structure==
==About this Structure==
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1OPL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Additional information on 1OPL is available in a page on [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb43_1.html Src Tyrosine Kinase] at the RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OPL OCA].
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1OPL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Src Tyrosine Kinase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_7 10.2210/rcsb_pdb/mom_2003_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OPL OCA].
==Reference==
==Reference==
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Structural basis for the autoinhibition of c-Abl tyrosine kinase., Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J, Cell. 2003 Mar 21;112(6):859-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12654251 12654251]
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<ref group="xtra">PMID:12654251</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Src Tyrosine Kinase]]
[[Category: Src Tyrosine Kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 10:44:30 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:58:49 2009''

Revision as of 22:58, 17 February 2009

Image:1opl.png


PDB ID 1opl

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1opl, resolution 3.42Å ()
Ligands: ,
Gene: Abl (Homo sapiens)
Activity: Transferase, with EC number and 2.7.10.2 2.7.10.1 and 2.7.10.2
Related: 1opj, 1opk
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Structural basis for the auto-inhibition of c-Abl tyrosine kinase

Template:ABSTRACT PUBMED 12654251

About this Structure

1OPL is a 2 chains structure of sequences from Homo sapiens. The July 2003 RCSB PDB Molecule of the Month feature on Src Tyrosine Kinase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2003_7. Full crystallographic information is available from OCA.

Reference

  • Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J. Structural basis for the autoinhibition of c-Abl tyrosine kinase. Cell. 2003 Mar 21;112(6):859-71. PMID:12654251

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