1jlb

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==About this Structure==
==About this Structure==
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1JLB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2) Human immunodeficiency virus type 1 (isolate hxb2)]. Additional information on 1JLB is available in a page on [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_1.html Reverse Transcriptase] at the RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLB OCA].
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1JLB is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2) Human immunodeficiency virus type 1 (isolate hxb2)]. The September 2002 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Reverse Transcriptase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2002_9 10.2210/rcsb_pdb/mom_2002_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLB OCA].
==Reference==
==Reference==
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Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors., Ren J, Nichols C, Bird L, Chamberlain P, Weaver K, Short S, Stuart DI, Stammers DK, J Mol Biol. 2001 Sep 28;312(4):795-805. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11575933 11575933]
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<ref group="xtra">PMID:11575933</ref><references group="xtra"/>
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[[Category: Protein complex]]
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[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
[[Category: Reverse Transcriptase]]
[[Category: Reverse Transcriptase]]
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[[Category: Non-nucleoside inhibitor]]
[[Category: Non-nucleoside inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 11:08:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:04:49 2009''

Revision as of 00:04, 17 February 2009

Image:1jlb.png

Template:STRUCTURE 1jlb

CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE

Template:ABSTRACT PUBMED 11575933

About this Structure

1JLB is a 2 chains structure of sequences from Human immunodeficiency virus type 1 (isolate hxb2). The September 2002 RCSB PDB Molecule of the Month feature on Reverse Transcriptase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_9. Full crystallographic information is available from OCA.

Reference

  • Ren J, Nichols C, Bird L, Chamberlain P, Weaver K, Short S, Stuart DI, Stammers DK. Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors. J Mol Biol. 2001 Sep 28;312(4):795-805. PMID:11575933 doi:http://dx.doi.org/10.1006/jmbi.2001.4988

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