2fx9

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==About this Structure==
==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FX9 OCA].
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2FX9 is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FX9 OCA].
==Reference==
==Reference==
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Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10., Cardoso RM, Brunel FM, Ferguson S, Zwick M, Burton DR, Dawson PE, Wilson IA, J Mol Biol. 2007 Feb 2;365(5):1533-44. Epub 2006 Nov 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17125793 17125793]
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<ref group="xtra">PMID:17125793</ref><ref group="xtra">PMID:15723805</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41., Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, Burton DR, Wilson IA, Immunity. 2005 Feb;22(2):163-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15723805 15723805]
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[[Category: Brunel, F M.]]
[[Category: Brunel, F M.]]
[[Category: Burton, D R.]]
[[Category: Burton, D R.]]
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[[Category: Immunoglobulin fold]]
[[Category: Immunoglobulin fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:59:04 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:21:12 2009''

Revision as of 12:21, 16 February 2009

Image:2fx9.png

Template:STRUCTURE 2fx9

Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41

Template:ABSTRACT PUBMED 17125793

About this Structure

2FX9 is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cardoso RM, Brunel FM, Ferguson S, Zwick M, Burton DR, Dawson PE, Wilson IA. Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. J Mol Biol. 2007 Feb 2;365(5):1533-44. Epub 2006 Nov 10. PMID:17125793 doi:10.1016/j.jmb.2006.10.088
  • Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, Burton DR, Wilson IA. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity. 2005 Feb;22(2):163-73. PMID:15723805 doi:10.1016/j.immuni.2004.12.011

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