2of2
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | 2OF2 is a | + | 2OF2 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OF2 OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:17276681</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Martin, M W.]] | [[Category: Martin, M W.]] | ||
[[Category: Kinase domain]] | [[Category: Kinase domain]] | ||
[[Category: Lck]] | [[Category: Lck]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:46:32 2009'' |
Revision as of 13:46, 16 February 2009
Contents |
crystal structure of furanopyrimidine 8 bound to lck
Template:ABSTRACT PUBMED 17276681
Disease
Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]
About this Structure
2OF2 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Martin MW, Newcomb J, Nunes JJ, Bemis JE, McGowan DC, White RD, Buchanan JL, DiMauro EF, Boucher C, Faust T, Hsieh F, Huang X, Lee JH, Schneider S, Turci SM, Zhu X. Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2299-304. Epub 2007 Jan 24. PMID:17276681 doi:10.1016/j.bmcl.2007.01.048
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