1o5d
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 1O5D is a | + | 1O5D is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O5D OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:15522303</ref><references group="xtra"/> | |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Protein complex]] | ||
[[Category: Chan, H.]] | [[Category: Chan, H.]] | ||
[[Category: Gjerstad, E.]] | [[Category: Gjerstad, E.]] | ||
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[[Category: Trypsin]] | [[Category: Trypsin]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:22:40 2009'' |
Revision as of 14:22, 16 February 2009
Contents |
Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)
Template:ABSTRACT PUBMED 15522303
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
1O5D is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Katz BA, Luong C, Ho JD, Somoza JR, Gjerstad E, Tang J, Williams SR, Verner E, Mackman RL, Young WB, Sprengeler PA, Chan H, Mortara K, Janc JW, McGrath ME. Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA). J Mol Biol. 2004 Nov 19;344(2):527-47. PMID:15522303 doi:10.1016/j.jmb.2004.09.032
Page seeded by OCA on Mon Feb 16 16:22:40 2009
Categories: Coagulation factor VIIa | Homo sapiens | Chan, H. | Gjerstad, E. | Ho, J D. | Janc, J W. | Katz, B A. | Luong, C. | Mackman, R L. | McGrath, M E. | Mortara, K. | Somoza, J R. | Sprengeler, P A. | Tang, J. | Verner, E. | Williams, S R. | Young, W B. | Ala190 upa | Conserved water displacement hydrogen bond deficit | Factor viia | Hepsin | S1 site | Selectivity | Thrombin | Trypsin