2oj9
From Proteopedia
(Difference between revisions)
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==Disease== | ==Disease== | ||
| - | Known disease associated with this structure: | + | Known disease associated with this structure: Insulin-like growth factor I, resistance to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147370 147370]] |
==About this Structure== | ==About this Structure== | ||
| - | 2OJ9 is a | + | 2OJ9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OJ9 OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:17317169</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Jacobson, B L.]] | [[Category: Jacobson, B L.]] | ||
| Line 36: | Line 35: | ||
[[Category: Kinase domain]] | [[Category: Kinase domain]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:37:41 2009'' |
Revision as of 14:37, 16 February 2009
Contents |
Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor
Template:ABSTRACT PUBMED 17317169
Disease
Known disease associated with this structure: Insulin-like growth factor I, resistance to OMIM:[147370]
About this Structure
2OJ9 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Velaparthi U, Wittman M, Liu P, Stoffan K, Zimmermann K, Sang X, Carboni J, Li A, Attar R, Gottardis M, Greer A, Chang CY, Jacobsen BL, Sack JS, Sun Y, Langley DR, Balasubramanian B, Vyas D. Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R). Bioorg Med Chem Lett. 2007 Apr 15;17(8):2317-21. Epub 2007 Feb 4. PMID:17317169 doi:10.1016/j.bmcl.2007.01.102
Page seeded by OCA on Mon Feb 16 16:37:41 2009
