3cro
From Proteopedia
(New page: 200px<br /><applet load="3cro" size="450" color="white" frame="true" align="right" spinBox="true" caption="3cro, resolution 2.500Å" /> '''THE PHAGE 434 CRO/O...) |
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| - | [[Image:3cro.jpg|left|200px]]<br /><applet load="3cro" size=" | + | [[Image:3cro.jpg|left|200px]]<br /><applet load="3cro" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="3cro, resolution 2.500Å" /> | caption="3cro, resolution 2.500Å" /> | ||
'''THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION'''<br /> | '''THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The crystal structure of phage 434 Cro protein in complex with a 20 | + | The crystal structure of phage 434 Cro protein in complex with a 20 base-pair DNA fragment has been determined to 2.5 A resolution. The DNA fragment contains the sequence of the OR1 operator site. The structure shows a bent conformation for the DNA, straighter at the center and more bent at the ends. The central base-pairs adopt conformations with significant deviations from coplanarity. The two molecules interact extensively along their common interface, both through hydrogen bonds and van der Waals interactions. The significance of these interactions for operator binding and recognition is discussed. |
==About this Structure== | ==About this Structure== | ||
| - | 3CRO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteriophage_434 Bacteriophage 434]. Full crystallographic information is available from [http:// | + | 3CRO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteriophage_434 Bacteriophage 434]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CRO OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Bacteriophage 434]] | [[Category: Bacteriophage 434]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Harrison, S | + | [[Category: Harrison, S C.]] |
[[Category: Mondragon, A.]] | [[Category: Mondragon, A.]] | ||
[[Category: double helix]] | [[Category: double helix]] | ||
[[Category: protein-dna complex]] | [[Category: protein-dna complex]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:08:58 2008'' |
Revision as of 17:09, 21 February 2008
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THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION
Overview
The crystal structure of phage 434 Cro protein in complex with a 20 base-pair DNA fragment has been determined to 2.5 A resolution. The DNA fragment contains the sequence of the OR1 operator site. The structure shows a bent conformation for the DNA, straighter at the center and more bent at the ends. The central base-pairs adopt conformations with significant deviations from coplanarity. The two molecules interact extensively along their common interface, both through hydrogen bonds and van der Waals interactions. The significance of these interactions for operator binding and recognition is discussed.
About this Structure
3CRO is a Single protein structure of sequence from Bacteriophage 434. Full crystallographic information is available from OCA.
Reference
The phage 434 Cro/OR1 complex at 2.5 A resolution., Mondragon A, Harrison SC, J Mol Biol. 1991 May 20;219(2):321-34. PMID:2038059
Page seeded by OCA on Thu Feb 21 19:08:58 2008
