2nm1

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==About this Structure==
==About this Structure==
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2NM1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NM1 OCA].
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2NM1 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NM1 OCA].
==Reference==
==Reference==
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Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity., Jin R, Rummel A, Binz T, Brunger AT, Nature. 2006 Dec 21;444(7122):1092-5. Epub 2006 Dec 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17167421 17167421]
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<ref group="xtra">PMID:17167421</ref><ref group="xtra">PMID:10932256</ref><ref group="xtra">PMID:15781237</ref><references group="xtra"/>
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Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B., Swaminathan S, Eswaramoorthy S, Nat Struct Biol. 2000 Aug;7(8):693-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10932256 10932256]
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N-terminal helix reorients in recombinant C-fragment of Clostridium botulinum type B., Jayaraman S, Eswaramoorthy S, Ahmed SA, Smith LA, Swaminathan S, Biochem Biophys Res Commun. 2005 Apr 29;330(1):97-103. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15781237 15781237]
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[[Category: Bontoxilysin]]
[[Category: Bontoxilysin]]
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Single protein]]
 
[[Category: Binz, T.]]
[[Category: Binz, T.]]
[[Category: Brunger, A T.]]
[[Category: Brunger, A T.]]
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[[Category: Synaptotagmin]]
[[Category: Synaptotagmin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:32:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:12:14 2009''

Revision as of 15:12, 16 February 2009

Image:2nm1.png

Template:STRUCTURE 2nm1

Structure of BoNT/B in complex with its protein receptor

Template:ABSTRACT PUBMED 17167421

About this Structure

2NM1 is a 2 chains structure of sequences from Clostridium botulinum and Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Jin R, Rummel A, Binz T, Brunger AT. Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity. Nature. 2006 Dec 21;444(7122):1092-5. Epub 2006 Dec 13. PMID:17167421 doi:http://dx.doi.org/10.1038/nature05387
  • Swaminathan S, Eswaramoorthy S. Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B. Nat Struct Biol. 2000 Aug;7(8):693-9. PMID:10932256
  • Jayaraman S, Eswaramoorthy S, Ahmed SA, Smith LA, Swaminathan S. N-terminal helix reorients in recombinant C-fragment of Clostridium botulinum type B. Biochem Biophys Res Commun. 2005 Apr 29;330(1):97-103. PMID:15781237 doi:http://dx.doi.org/10.1016/j.bbrc.2005.02.123

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