2anq
From Proteopedia
(Difference between revisions)
Line 20: | Line 20: | ||
==About this Structure== | ==About this Structure== | ||
- | 2ANQ is a | + | 2ANQ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANQ OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:17125251</ref><references group="xtra"/> | |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
- | [[Category: Single protein]] | ||
[[Category: Brown, E D.]] | [[Category: Brown, E D.]] | ||
[[Category: Daigle, D M.]] | [[Category: Daigle, D M.]] | ||
Line 38: | Line 37: | ||
[[Category: Protein inhibitor complex]] | [[Category: Protein inhibitor complex]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:25:12 2009'' |
Revision as of 16:25, 16 February 2009
Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.
Template:ABSTRACT PUBMED 17125251
About this Structure
2ANQ is a 1 chain structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:17125251 doi:10.1021/jm060570v
Page seeded by OCA on Mon Feb 16 18:25:12 2009