2anq

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==About this Structure==
==About this Structure==
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2ANQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANQ OCA].
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2ANQ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANQ OCA].
==Reference==
==Reference==
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A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region., Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS, J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17125251 17125251]
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<ref group="xtra">PMID:17125251</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
 
[[Category: Brown, E D.]]
[[Category: Brown, E D.]]
[[Category: Daigle, D M.]]
[[Category: Daigle, D M.]]
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[[Category: Protein inhibitor complex]]
[[Category: Protein inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 22:29:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:25:12 2009''

Revision as of 16:25, 16 February 2009

Template:STRUCTURE 2anq

Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.

Template:ABSTRACT PUBMED 17125251

About this Structure

2ANQ is a 1 chain structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:17125251 doi:10.1021/jm060570v

Page seeded by OCA on Mon Feb 16 18:25:12 2009

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