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1q2p

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==About this Structure==
==About this Structure==
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1Q2P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q2P OCA].
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1Q2P is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q2P OCA].
==Reference==
==Reference==
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Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates., Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR, J Med Chem. 2004 Dec 16;47(26):6556-68. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15588091 15588091]
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<ref group="xtra">PMID:15588091</ref><references group="xtra"/>
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
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[[Category: Single protein]]
 
[[Category: Bonomo, R A.]]
[[Category: Bonomo, R A.]]
[[Category: Hujer, A.]]
[[Category: Hujer, A.]]
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[[Category: Inhibition]]
[[Category: Inhibition]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 22:49:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:35:40 2009''

Revision as of 16:35, 16 February 2009

Image:1q2p.png

Template:STRUCTURE 1q2p

SHV-1 class A beta-lactamase complexed with penem WAY185229

Template:ABSTRACT PUBMED 15588091

About this Structure

1Q2P is a 1 chain structure of sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA.

Reference

  • Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR. Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates. J Med Chem. 2004 Dec 16;47(26):6556-68. PMID:15588091 doi:10.1021/jm049680x

Page seeded by OCA on Mon Feb 16 18:35:40 2009

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