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2ibt

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==About this Structure==
==About this Structure==
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2IBT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IBT OCA].
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2IBT is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IBT OCA].
==Reference==
==Reference==
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2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI: crystal structures and time-resolved fluorescence., Lenz T, Bonnist EY, Pljevaljcic G, Neely RK, Dryden DT, Scheidig AJ, Jones AC, Weinhold E, J Am Chem Soc. 2007 May 16;129(19):6240-8. Epub 2007 Apr 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17455934 17455934]
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<ref group="xtra">PMID:17455934</ref><ref group="xtra">PMID:11175890</ref><ref group="xtra">PMID:8995524</ref><references group="xtra"/>
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A Taq attack displaces bases., Blumenthal RM, Cheng X, Nat Struct Biol. 2001 Feb;8(2):101-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11175890 11175890]
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Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI., Schluckebier G, Kozak M, Bleimling N, Weinhold E, Saenger W, J Mol Biol. 1997 Jan 10;265(1):56-67. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8995524 8995524]
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[[Category: Single protein]]
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[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
[[Category: Lenz, T.]]
[[Category: Lenz, T.]]
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[[Category: Nucleotide flipping]]
[[Category: Nucleotide flipping]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:14:04 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:54:46 2009''

Revision as of 16:54, 16 February 2009

Image:2ibt.png

Template:STRUCTURE 2ibt

Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position and an abasic site analog at the target base partner position

Template:ABSTRACT PUBMED 17455934

About this Structure

2IBT is a 6 chains structure of sequences from Thermus aquaticus. Full crystallographic information is available from OCA.

Reference

  • Lenz T, Bonnist EY, Pljevaljcic G, Neely RK, Dryden DT, Scheidig AJ, Jones AC, Weinhold E. 2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI: crystal structures and time-resolved fluorescence. J Am Chem Soc. 2007 May 16;129(19):6240-8. Epub 2007 Apr 25. PMID:17455934 doi:http://dx.doi.org/10.1021/ja069366n
  • Blumenthal RM, Cheng X. A Taq attack displaces bases. Nat Struct Biol. 2001 Feb;8(2):101-3. PMID:11175890 doi:http://dx.doi.org/10.1038/84072
  • Schluckebier G, Kozak M, Bleimling N, Weinhold E, Saenger W. Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI. J Mol Biol. 1997 Jan 10;265(1):56-67. PMID:8995524 doi:http://dx.doi.org/10.1006/jmbi.1996.0711

Page seeded by OCA on Mon Feb 16 18:54:46 2009

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