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1yy9
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 1YY9 is a | + | 1YY9 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus/homo_sapiens Mus musculus/homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YY9 OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:15837620</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mus musculus/homo sapiens]] | [[Category: Mus musculus/homo sapiens]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Ferguson, K M.]] | [[Category: Ferguson, K M.]] | ||
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[[Category: Tyrosine kinase]] | [[Category: Tyrosine kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:30:08 2009'' |
Revision as of 17:30, 16 February 2009
Contents |
Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
Template:ABSTRACT PUBMED 15837620
Disease
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this Structure
1YY9 is a 3 chains structure of sequences from Homo sapiens and Mus musculus/homo sapiens. Full crystallographic information is available from OCA.
Reference
- Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell. 2005 Apr;7(4):301-11. PMID:15837620 doi:10.1016/j.ccr.2005.03.003
Page seeded by OCA on Mon Feb 16 19:30:08 2009
