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2hwh

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==About this Structure==
==About this Structure==
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2HWH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HWH OCA].
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2HWH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HWH OCA].
==Reference==
==Reference==
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Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors., Yan S, Appleby T, Larson G, Wu JZ, Hamatake R, Hong Z, Yao N, Bioorg Med Chem Lett. 2006 Nov 15;16(22):5888-91. Epub 2006 Aug 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16934455 16934455]
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<ref group="xtra">PMID:16934455</ref><references group="xtra"/>
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
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[[Category: Single protein]]
 
[[Category: Yao, N.]]
[[Category: Yao, N.]]
[[Category: Allosteric inhibitor]]
[[Category: Allosteric inhibitor]]
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[[Category: Viral rna-directed rna polymerase]]
[[Category: Viral rna-directed rna polymerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:30:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:20:58 2009''

Revision as of 18:21, 16 February 2009

Image:2hwh.png

Template:STRUCTURE 2hwh

HCV NS5B allosteric inhibitor complex

Template:ABSTRACT PUBMED 16934455

About this Structure

2HWH is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Yan S, Appleby T, Larson G, Wu JZ, Hamatake R, Hong Z, Yao N. Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5888-91. Epub 2006 Aug 24. PMID:16934455 doi:10.1016/j.bmcl.2006.08.056

Page seeded by OCA on Mon Feb 16 20:20:58 2009

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