2g94
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 2G94 is a | + | 2G94 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G94 OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:16620080</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
- | [[Category: Single protein]] | ||
[[Category: Ghosh, A.]] | [[Category: Ghosh, A.]] | ||
[[Category: Hong, L.]] | [[Category: Hong, L.]] | ||
Line 39: | Line 38: | ||
[[Category: Protease inhibitor]] | [[Category: Protease inhibitor]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:58:52 2009'' |
Revision as of 18:58, 16 February 2009
Crystal structure of beta-secretase bound to a potent and highly selective inhibitor.
Template:ABSTRACT PUBMED 16620080
About this Structure
2G94 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Ghosh AK, Kumaragurubaran N, Hong L, Lei H, Hussain KA, Liu CF, Devasamudram T, Weerasena V, Turner R, Koelsch G, Bilcer G, Tang J. Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. J Am Chem Soc. 2006 Apr 26;128(16):5310-1. PMID:16620080 doi:10.1021/ja058636j
Page seeded by OCA on Mon Feb 16 20:58:52 2009
Categories: Homo sapiens | Memapsin 2 | Ghosh, A. | Hong, L. | Tang, J. | Alzheimer's disease | Asp2 | Aspartic protease | Bace | Beta secretase | Drug design | Memapsin | Protease inhibitor