2dxs

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==About this Structure==
==About this Structure==
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2DXS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXS OCA].
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2DXS is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXS OCA].
==Reference==
==Reference==
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Discovery of conformationally constrained tetracyclic compounds as potent hepatitis C virus NS5B RNA polymerase inhibitors., Ikegashira K, Oka T, Hirashima S, Noji S, Yamanaka H, Hara Y, Adachi T, Tsuruha J, Doi S, Hase Y, Noguchi T, Ando I, Ogura N, Ikeda S, Hashimoto H, J Med Chem. 2006 Nov 30;49(24):6950-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17125247 17125247]
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<ref group="xtra">PMID:17125247</ref><references group="xtra"/>
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
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[[Category: Single protein]]
 
[[Category: Adachi, T.]]
[[Category: Adachi, T.]]
[[Category: Doi, S.]]
[[Category: Doi, S.]]
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[[Category: Rna polymerase]]
[[Category: Rna polymerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 01:42:30 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:04:30 2009''

Revision as of 19:04, 16 February 2009

Template:STRUCTURE 2dxs

Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor

Template:ABSTRACT PUBMED 17125247

About this Structure

2DXS is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Ikegashira K, Oka T, Hirashima S, Noji S, Yamanaka H, Hara Y, Adachi T, Tsuruha J, Doi S, Hase Y, Noguchi T, Ando I, Ogura N, Ikeda S, Hashimoto H. Discovery of conformationally constrained tetracyclic compounds as potent hepatitis C virus NS5B RNA polymerase inhibitors. J Med Chem. 2006 Nov 30;49(24):6950-3. PMID:17125247 doi:10.1021/jm0610245

Page seeded by OCA on Mon Feb 16 21:04:30 2009

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