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2o8b

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==About this Structure==
==About this Structure==
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2O8B is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8B OCA].
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2O8B is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8B OCA].
==Reference==
==Reference==
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Structure of the human MutSalpha DNA lesion recognition complex., Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS, Mol Cell. 2007 May 25;26(4):579-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17531815 17531815]
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<ref group="xtra">PMID:17531815</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Beese, L S.]]
[[Category: Beese, L S.]]
[[Category: Changela, A.]]
[[Category: Changela, A.]]
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[[Category: Somatic hypermutation]]
[[Category: Somatic hypermutation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:54:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:37:02 2009''

Revision as of 21:37, 16 February 2009

Image:2o8b.png

Template:STRUCTURE 2o8b

Contents

human MutSalpha (MSH2/MSH6) bound to ADP and a G T mispair

Template:ABSTRACT PUBMED 17531815

Disease

Known disease associated with this structure: Colorectal cancer, hereditary nonpolyposis, type 1 OMIM:[609309], Mismatch repair cancer syndrome OMIM:[609309], Muir-Torre syndrome OMIM:[609309]

About this Structure

2O8B is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS. Structure of the human MutSalpha DNA lesion recognition complex. Mol Cell. 2007 May 25;26(4):579-92. PMID:17531815 doi:10.1016/j.molcel.2007.04.018

Page seeded by OCA on Mon Feb 16 23:37:02 2009

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