1lqa
From Proteopedia
(New page: 200px<br /><applet load="1lqa" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lqa, resolution 1.604Å" /> '''TAS PROTEIN FROM ES...) |
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| - | [[Image:1lqa.jpg|left|200px]]<br /><applet load="1lqa" size=" | + | [[Image:1lqa.jpg|left|200px]]<br /><applet load="1lqa" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1lqa, resolution 1.604Å" /> | caption="1lqa, resolution 1.604Å" /> | ||
'''TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH'''<br /> | '''TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH'''<br /> | ||
==Overview== | ==Overview== | ||
| - | BACKGROUND: The protein encoded by the gene ybgI was chosen as a target | + | BACKGROUND: The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function. RESULTS: The structure of the ybgI protein is a toroid composed of six polypeptide chains forming a trimer of dimers. Each polypeptide chain binds two metal ions on the inside of the toroid. CONCLUSION: The toroidal structure is comparable to that of some proteins that are involved in DNA metabolism. The di-nuclear metal site could imply that the specific function of this protein is as a hydrolase-oxidase enzyme. |
==About this Structure== | ==About this Structure== | ||
| - | 1LQA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with NDP as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1LQA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=NDP:'>NDP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQA OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Camerini-Otero, R | + | [[Category: Camerini-Otero, R D.]] |
| - | [[Category: Gilliland, G | + | [[Category: Gilliland, G L.]] |
| - | [[Category: Howard, A | + | [[Category: Howard, A J.]] |
| - | [[Category: Khil, P | + | [[Category: Khil, P P.]] |
[[Category: Obmolova, G.]] | [[Category: Obmolova, G.]] | ||
| - | [[Category: S2F, Structure | + | [[Category: S2F, Structure 2.Function Project.]] |
[[Category: Teplyakov, A.]] | [[Category: Teplyakov, A.]] | ||
[[Category: NDP]] | [[Category: NDP]] | ||
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[[Category: tim barrel]] | [[Category: tim barrel]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:47:22 2008'' |
Revision as of 11:47, 21 February 2008
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TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH
Overview
BACKGROUND: The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function. RESULTS: The structure of the ybgI protein is a toroid composed of six polypeptide chains forming a trimer of dimers. Each polypeptide chain binds two metal ions on the inside of the toroid. CONCLUSION: The toroidal structure is comparable to that of some proteins that are involved in DNA metabolism. The di-nuclear metal site could imply that the specific function of this protein is as a hydrolase-oxidase enzyme.
About this Structure
1LQA is a Single protein structure of sequence from Escherichia coli with as ligand. Full crystallographic information is available from OCA.
Reference
Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site., Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, Camerini-Otero RD, Gilliland GL, BMC Struct Biol. 2003 Sep 30;3:7. PMID:14519207
Page seeded by OCA on Thu Feb 21 13:47:22 2008
