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1lxd
From Proteopedia
(New page: 200px<br /><applet load="1lxd" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lxd, resolution 2.4Å" /> '''CRYSTAL STRUCTURE OF ...) |
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| - | [[Image:1lxd.gif|left|200px]]<br /><applet load="1lxd" size=" | + | [[Image:1lxd.gif|left|200px]]<br /><applet load="1lxd" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1lxd, resolution 2.4Å" /> | caption="1lxd, resolution 2.4Å" /> | ||
'''CRYSTAL STRUCTURE OF THE RAS INTERACTING DOMAIN OF RALGDS, A GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR OF RAL PROTEIN'''<br /> | '''CRYSTAL STRUCTURE OF THE RAS INTERACTING DOMAIN OF RALGDS, A GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR OF RAL PROTEIN'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The Ras-interacting domains of the the protein-kinase Raf and the Ral | + | The Ras-interacting domains of the the protein-kinase Raf and the Ral guanine nucleotide dissociation stimulator, RalGDS, lack extensive sequence similarity, but their overall three-dimensional structures are very similar to each other. Mutational analysis indicated that three residues in the RalGDS domain are critical for its interaction with Ras. |
==About this Structure== | ==About this Structure== | ||
| - | 1LXD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http:// | + | 1LXD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LXD OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Hofer, F.]] | [[Category: Hofer, F.]] | ||
[[Category: Huang, L.]] | [[Category: Huang, L.]] | ||
| - | [[Category: Kim, S | + | [[Category: Kim, S H.]] |
| - | [[Category: Martin, G | + | [[Category: Martin, G S.]] |
| - | [[Category: Weng, X | + | [[Category: Weng, X W.]] |
[[Category: cdc25 family]] | [[Category: cdc25 family]] | ||
[[Category: cross-talk]] | [[Category: cross-talk]] | ||
| Line 26: | Line 26: | ||
[[Category: ubiquitin fold]] | [[Category: ubiquitin fold]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:49:19 2008'' |
Revision as of 11:49, 21 February 2008
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CRYSTAL STRUCTURE OF THE RAS INTERACTING DOMAIN OF RALGDS, A GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR OF RAL PROTEIN
Overview
The Ras-interacting domains of the the protein-kinase Raf and the Ral guanine nucleotide dissociation stimulator, RalGDS, lack extensive sequence similarity, but their overall three-dimensional structures are very similar to each other. Mutational analysis indicated that three residues in the RalGDS domain are critical for its interaction with Ras.
About this Structure
1LXD is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
Three-dimensional structure of the Ras-interacting domain of RalGDS., Huang L, Weng X, Hofer F, Martin GS, Kim SH, Nat Struct Biol. 1997 Aug;4(8):609-15. PMID:9253406
Page seeded by OCA on Thu Feb 21 13:49:19 2008
