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1gt1

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(New page: 200px<br /> <applet load="1gt1" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gt1, resolution 1.71&Aring;" /> '''COMPLEX OF BOVINE O...)
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==About this Structure==
==About this Structure==
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1GT1 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] with PRZ and ANC as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GT1 OCA]].
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1GT1 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] with PRZ and ANC as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: PRZ. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GT1 OCA]].
==Reference==
==Reference==
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[[Category: lipocalin]]
[[Category: lipocalin]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 20:25:38 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:18:02 2007''

Revision as of 11:13, 30 October 2007

Image:1gt1.gif

1gt1, resolution 1.71Å

Drag the structure with the mouse to rotate

COMPLEX OF BOVINE ODORANT BINDING PROTEIN WITH AMINOANTHRACENE AND PYRAZINE

Overview

The structure of bovine odorant-binding protein (bOBP) revealed a striking, feature of a dimer formed by domain swapping [Tegoni, M., Ramoni, R., Bignetti, E., Spinelli, S. & Cambillau, C. (1996) Nat. Struct. Biol.3, 863-867; Bianchet, M.A., Bains, G., Pelosi, P., Pevsner, J., Snyder, S.H., Monaco, H.L. & Amzel, L.M. (1996) Nat. Struct. Biol.3, 934-939] and the, presence of a naturally occuring ligand [Ramoni, R., Vincent, F., Grolli, S., Conti, V., Malosse, C., Boyer, F.D., Nagnan-Le Meillour, P., Spinelli, S., Cambillau, C. & Tegoni, M. (2001) J. Biol. Chem.276, 7150-7155]. These, features led us to investigate the binding of odorant molecules with bOBP, in solution and in the crystal. The behavior of odorant molecules in bOBP, resembles that observed with porcine OBP ... [(full description)]

About this Structure

1GT1 is a [Single protein] structure of sequence from [Bos taurus] with PRZ and ANC as [ligands]. Structure known Active Site: PRZ. Full crystallographic information is available from [OCA].

Reference

Crystal structures of bovine odorant-binding protein in complex with odorant molecules., Vincent F, Ramoni R, Spinelli S, Grolli S, Tegoni M, Cambillau C, Eur J Biochem. 2004 Oct;271(19):3832-42. PMID:15373829

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