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3bw5

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==About this Structure==
==About this Structure==
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3BW5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ymi 1ymi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BW5 OCA].
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3BW5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ymi 1ymi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BW5 OCA].
==Reference==
==Reference==
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The CK2alpha/CK2beta Interface of Human Protein Kinase CK2 Harbors a Binding Pocket for Small Molecules., Raaf J, Brunstein E, Issinger OG, Niefind K, Chem Biol. 2008 Feb;15(2):111-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18291315 18291315]
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<ref group="xtra">PMID:18291315</ref><ref group="xtra">PMID:15740749</ref><references group="xtra"/>
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Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate., Yde CW, Ermakova I, Issinger OG, Niefind K, J Mol Biol. 2005 Mar 25;347(2):399-414. Epub 2005 Jan 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15740749 15740749]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
 
[[Category: Ermakova, I.]]
[[Category: Ermakova, I.]]
[[Category: Issinger, O G.]]
[[Category: Issinger, O G.]]
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[[Category: Wnt signaling pathway]]
[[Category: Wnt signaling pathway]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:42:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:12:18 2009''

Revision as of 04:12, 17 February 2009

Image:3bw5.png

Template:STRUCTURE 3bw5

Crystal structure of a mutant of human protein kinase CK2alpha with altered cosubstrate specificity

Template:ABSTRACT PUBMED 18291315

About this Structure

3BW5 is a 1 chain structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1ymi. Full crystallographic information is available from OCA.

Reference

  • Raaf J, Brunstein E, Issinger OG, Niefind K. The CK2 alpha/CK2 beta interface of human protein kinase CK2 harbors a binding pocket for small molecules. Chem Biol. 2008 Feb;15(2):111-7. PMID:18291315 doi:http://dx.doi.org/10.1016/j.chembiol.2007.12.012
  • Yde CW, Ermakova I, Issinger OG, Niefind K. Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate. J Mol Biol. 2005 Mar 25;347(2):399-414. Epub 2005 Jan 18. PMID:15740749 doi:http://dx.doi.org/10.1016/j.jmb.2005.01.003

Page seeded by OCA on Tue Feb 17 06:12:18 2009

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