2acu
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 2ACU is a | + | 2ACU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ACU OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:8117659</ref><references group="xtra"/> | |
[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Single protein]] | ||
[[Category: Bohren, K M.]] | [[Category: Bohren, K M.]] | ||
[[Category: Gabbay, K H.]] | [[Category: Gabbay, K H.]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:37:56 2009'' |
Revision as of 04:37, 17 February 2009
TYROSINE-48 IS THE PROTON DONOR AND HISTIDINE-110 DIRECTS SUBSTRATE STEREOCHEMICAL SELECTIVITY IN THE REDUCTION REACTION OF HUMAN ALDOSE REDUCTASE: ENZYME KINETICS AND THE CRYSTAL STRUCTURE OF THE Y48H MUTANT ENZYME
Template:ABSTRACT PUBMED 8117659
About this Structure
2ACU is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bohren KM, Grimshaw CE, Lai CJ, Harrison DH, Ringe D, Petsko GA, Gabbay KH. Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme. Biochemistry. 1994 Mar 1;33(8):2021-32. PMID:8117659
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