2rl5

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==About this Structure==
==About this Structure==
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2RL5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RL5 OCA].
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2RL5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RL5 OCA].
==Reference==
==Reference==
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Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis., La DS, Belzile J, Bready JV, Coxon A, Demelfi T, Doerr N, Estrada J, Flynn JC, Flynn SR, Graceffa RF, Harriman SP, Larrow JF, Long AM, Martin MW, Morrison MJ, Patel VF, Roveto PM, Wang L, Weiss MM, Whittington DA, Teffera Y, Zhao Z, Polverino AJ, Harmange JC, J Med Chem. 2008 Mar 27;51(6):1695-705. Epub 2008 Feb 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18311900 18311900]
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<ref group="xtra">PMID:18311900</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Single protein]]
 
[[Category: Long, A M.]]
[[Category: Long, A M.]]
[[Category: Rose, P.]]
[[Category: Rose, P.]]
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[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:06:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:45:52 2009''

Revision as of 05:45, 17 February 2009

Image:2rl5.png

Template:STRUCTURE 2rl5

Crystal structure of the VEGFR2 kinase domain in complex with a 2,3-dihydro-1,4-benzoxazine inhibitor

Template:ABSTRACT PUBMED 18311900

About this Structure

2RL5 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • La DS, Belzile J, Bready JV, Coxon A, Demelfi T, Doerr N, Estrada J, Flynn JC, Flynn SR, Graceffa RF, Harriman SP, Larrow JF, Long AM, Martin MW, Morrison MJ, Patel VF, Roveto PM, Wang L, Weiss MM, Whittington DA, Teffera Y, Zhao Z, Polverino AJ, Harmange JC. Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis. J Med Chem. 2008 Mar 27;51(6):1695-705. Epub 2008 Feb 27. PMID:18311900 doi:10.1021/jm701129j

Page seeded by OCA on Tue Feb 17 07:45:52 2009

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