1zs0
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 1ZS0 is a | + | 1ZS0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZS0 OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:16451058</ref><ref group="xtra">PMID:10422833</ref><ref group="xtra">PMID:10978185</ref><ref group="xtra">PMID:7737183</ref><references group="xtra"/> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Neutrophil collagenase]] | [[Category: Neutrophil collagenase]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Agamennone, M.]] | [[Category: Agamennone, M.]] | ||
[[Category: Campestre, C.]] | [[Category: Campestre, C.]] | ||
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[[Category: Sulphonamide junction]] | [[Category: Sulphonamide junction]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:08:54 2009'' |
Revision as of 06:08, 17 February 2009
Crystal structure of the complex between MMP-8 and a phosphonate inhibitor (S-enantiomer)
Template:ABSTRACT PUBMED 16451058
About this Structure
1ZS0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pochetti G, Gavuzzo E, Campestre C, Agamennone M, Tortorella P, Consalvi V, Gallina C, Hiller O, Tschesche H, Tucker PA, Mazza F. Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates. J Med Chem. 2006 Feb 9;49(3):923-31. PMID:16451058 doi:10.1021/jm050787+
- Pavlovsky AG, Williams MG, Ye QZ, Ortwine DF, Purchase CF 2nd, White AD, Dhanaraj V, Roth BD, Johnson LL, Hupe D, Humblet C, Blundell TL. X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity. Protein Sci. 1999 Jul;8(7):1455-62. PMID:10422833
- Gavuzzo E, Pochetti G, Mazza F, Gallina C, Gorini B, D'Alessio S, Pieper M, Tschesche H, Tucker PA. Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design. J Med Chem. 2000 Sep 7;43(18):3377-85. PMID:10978185
- Grams F, Reinemer P, Powers JC, Kleine T, Pieper M, Tschesche H, Huber R, Bode W. X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design. Eur J Biochem. 1995 Mar 15;228(3):830-41. PMID:7737183
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