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1n56

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(New page: 200px<br /><applet load="1n56" size="450" color="white" frame="true" align="right" spinBox="true" caption="1n56, resolution 2.4&Aring;" /> '''Y-family DNA polymera...)
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[[Image:1n56.gif|left|200px]]<br /><applet load="1n56" size="450" color="white" frame="true" align="right" spinBox="true"
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[[Image:1n56.gif|left|200px]]<br /><applet load="1n56" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1n56, resolution 2.4&Aring;" />
caption="1n56, resolution 2.4&Aring;" />
'''Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion'''<br />
'''Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion'''<br />
==Overview==
==Overview==
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Studies on several recently discovered error-prone DNA polymerases reveal, novel structures that may explain the low fidelity of this general class, of enzymes, a number of which are involved in the replicative bypass, (translesion synthesis) of base damage in DNA.
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Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.
==About this Structure==
==About this Structure==
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1N56 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus] with MG, CA and ATP as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1N56 OCA].
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1N56 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=ATP:'>ATP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N56 OCA].
==Reference==
==Reference==
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[[Category: y-family]]
[[Category: y-family]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 21:58:15 2007''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:02:24 2008''

Revision as of 12:02, 21 February 2008

Image:1n56.gif

1n56, resolution 2.4Å

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Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion

Overview

Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.

About this Structure

1N56 is a Single protein structure of sequence from Sulfolobus solfataricus with , and as ligands. Full crystallographic information is available from OCA.

Reference

Error-prone DNA polymerases: novel structures and the benefits of infidelity., Friedberg EC, Fischhaber PL, Kisker C, Cell. 2001 Oct 5;107(1):9-12. PMID:11595180

Page seeded by OCA on Thu Feb 21 14:02:24 2008

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