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1szm

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==About this Structure==
==About this Structure==
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1SZM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZM OCA].
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1SZM is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZM OCA].
==Reference==
==Reference==
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The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A., Gassel M, Breitenlechner CB, Konig N, Huber R, Engh RA, Bossemeyer D, J Biol Chem. 2004 May 28;279(22):23679-90. Epub 2004 Mar 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14996846 14996846]
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<ref group="xtra">PMID:14996846</ref><ref group="xtra">PMID:9438863</ref><references group="xtra"/>
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Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential., Prade L, Engh RA, Girod A, Kinzel V, Huber R, Bossemeyer D, Structure. 1997 Dec 15;5(12):1627-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9438863 9438863]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
 
[[Category: Bossemeyer, D.]]
[[Category: Bossemeyer, D.]]
[[Category: Breitenlechner, C B.]]
[[Category: Breitenlechner, C B.]]
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[[Category: X-ray structure]]
[[Category: X-ray structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:34:54 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:29:26 2009''

Revision as of 09:29, 17 February 2009

Image:1szm.png

Template:STRUCTURE 1szm

DUAL BINDING MODE OF BISINDOLYLMALEIMIDE 2 TO PROTEIN KINASE A (PKA)

Template:ABSTRACT PUBMED 14996846

About this Structure

1SZM is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Gassel M, Breitenlechner CB, Konig N, Huber R, Engh RA, Bossemeyer D. The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. J Biol Chem. 2004 May 28;279(22):23679-90. Epub 2004 Mar 1. PMID:14996846 doi:10.1074/jbc.M314082200
  • Prade L, Engh RA, Girod A, Kinzel V, Huber R, Bossemeyer D. Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential. Structure. 1997 Dec 15;5(12):1627-37. PMID:9438863

Page seeded by OCA on Tue Feb 17 11:29:26 2009

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