1pwq

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[[Image:1pwq.png|left|200px]]
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{{STRUCTURE_1pwq| PDB=1pwq | SCENE= }}
{{STRUCTURE_1pwq| PDB=1pwq | SCENE= }}
===Crystal structure of Anthrax Lethal Factor complexed with Thioacetyl-Tyr-Pro-Met-Amide, a metal-chelating peptidyl small molecule inhibitor===
===Crystal structure of Anthrax Lethal Factor complexed with Thioacetyl-Tyr-Pro-Met-Amide, a metal-chelating peptidyl small molecule inhibitor===
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{{ABSTRACT_PUBMED_14718924}}
{{ABSTRACT_PUBMED_14718924}}
==About this Structure==
==About this Structure==
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1PWQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PWQ OCA].
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[[1pwq]] is a 2 chain structure of [[Anthrax Lethal Factor]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PWQ OCA].
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==See Also==
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*[[Anthrax Lethal Factor|Anthrax Lethal Factor]]
==Reference==
==Reference==
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The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor., Turk BE, Wong TY, Schwarzenbacher R, Jarrell ET, Leppla SH, Collier RJ, Liddington RC, Cantley LC, Nat Struct Mol Biol. 2004 Jan;11(1):60-6. Epub 2003 Dec 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14718924 14718924]
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<ref group="xtra">PMID:014718924</ref><references group="xtra"/>
[[Category: Anthrax lethal factor endopeptidase]]
[[Category: Anthrax lethal factor endopeptidase]]
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: Single protein]]
 
[[Category: Liddington, R C.]]
[[Category: Liddington, R C.]]
[[Category: Schwarzenbacher, R.]]
[[Category: Schwarzenbacher, R.]]
[[Category: Wong, T Y.]]
[[Category: Wong, T Y.]]
[[Category: Anthrax toxin]]
[[Category: Anthrax toxin]]
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[[Category: Hydrolase]]
[[Category: Lethal factor]]
[[Category: Lethal factor]]
[[Category: Metal-chelator]]
[[Category: Metal-chelator]]
[[Category: Small molecule peptidic inhibitor]]
[[Category: Small molecule peptidic inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:52:05 2008''
 

Revision as of 15:53, 26 July 2012

Template:STRUCTURE 1pwq

Contents

Crystal structure of Anthrax Lethal Factor complexed with Thioacetyl-Tyr-Pro-Met-Amide, a metal-chelating peptidyl small molecule inhibitor

Template:ABSTRACT PUBMED 14718924

About this Structure

1pwq is a 2 chain structure of Anthrax Lethal Factor with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

See Also

Reference

  • Turk BE, Wong TY, Schwarzenbacher R, Jarrell ET, Leppla SH, Collier RJ, Liddington RC, Cantley LC. The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat Struct Mol Biol. 2004 Jan;11(1):60-6. Epub 2003 Dec 29. PMID:14718924 doi:10.1038/nsmb708

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