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3c1x
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 3C1X is a | + | 3C1X is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C1X OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:18289854</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Sack, J.]] | [[Category: Sack, J.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
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[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:59:27 2009'' |
Revision as of 09:59, 17 February 2009
Contents |
Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-MET in complex with a Pyrrolotriazine based inhibitor
Template:ABSTRACT PUBMED 18289854
Disease
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]
About this Structure
3C1X is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Schroeder GM, Chen XT, Williams DK, Nirschl DS, Cai ZW, Wei D, Tokarski JS, An Y, Sack J, Chen Z, Huynh T, Vaccaro W, Poss M, Wautlet B, Gullo-Brown J, Kellar K, Manne V, Hunt JT, Wong TW, Lombardo LJ, Fargnoli J, Borzilleri RM. Identification of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of Met kinase. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1945-51. Epub 2008 Feb 7. PMID:18289854 doi:10.1016/j.bmcl.2008.01.121
Page seeded by OCA on Tue Feb 17 11:59:27 2009
