This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1r49

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 23: Line 23:
==About this Structure==
==About this Structure==
-
1R49 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R49 OCA].
+
1R49 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R49 OCA].
==Reference==
==Reference==
-
The role of lysine 532 in the catalytic mechanism of human topoisomerase I., Interthal H, Quigley PM, Hol WG, Champoux JJ, J Biol Chem. 2004 Jan 23;279(4):2984-92. Epub 2003 Oct 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14594810 14594810]
+
<ref group="xtra">PMID:14594810</ref><references group="xtra"/>
[[Category: DNA topoisomerase]]
[[Category: DNA topoisomerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
 
[[Category: Champoux, J J.]]
[[Category: Champoux, J J.]]
[[Category: Hol, W G.]]
[[Category: Hol, W G.]]
Line 38: Line 37:
[[Category: Topoisomerase i]]
[[Category: Topoisomerase i]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 17:05:04 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:41:38 2009''

Revision as of 10:41, 17 February 2009

Image:1r49.png

Template:STRUCTURE 1r49

Contents

Human topoisomerase I (Topo70) double mutant K532R/Y723F

Template:ABSTRACT PUBMED 14594810

Disease

Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[126420]

About this Structure

1R49 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Interthal H, Quigley PM, Hol WG, Champoux JJ. The role of lysine 532 in the catalytic mechanism of human topoisomerase I. J Biol Chem. 2004 Jan 23;279(4):2984-92. Epub 2003 Oct 31. PMID:14594810 doi:10.1074/jbc.M309959200

Page seeded by OCA on Tue Feb 17 12:41:38 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1r49"
Personal tools