2qyf

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==About this Structure==
==About this Structure==
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2QYF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QYF OCA].
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2QYF is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QYF OCA].
==Reference==
==Reference==
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p31comet blocks Mad2 activation through structural mimicry., Yang M, Li B, Tomchick DR, Machius M, Rizo J, Yu H, Luo X, Cell. 2007 Nov 16;131(4):744-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18022368 18022368]
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<ref group="xtra">PMID:18022368</ref><ref group="xtra">PMID:15024386</ref><ref group="xtra">PMID:11804586</ref><ref group="xtra">PMID:10700282</ref><references group="xtra"/>
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The Mad2 spindle checkpoint protein has two distinct natively folded states., Luo X, Tang Z, Xia G, Wassmann K, Matsumoto T, Rizo J, Yu H, Nat Struct Mol Biol. 2004 Apr;11(4):338-45. Epub 2004 Mar 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15024386 15024386]
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The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20., Luo X, Tang Z, Rizo J, Yu H, Mol Cell. 2002 Jan;9(1):59-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11804586 11804586]
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Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20., Luo X, Fang G, Coldiron M, Lin Y, Yu H, Kirschner MW, Wagner G, Nat Struct Biol. 2000 Mar;7(3):224-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10700282 10700282]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Luo, X.]]
[[Category: Luo, X.]]
[[Category: Tomchick, D R.]]
[[Category: Tomchick, D R.]]
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[[Category: Spindle assembly checkpoint]]
[[Category: Spindle assembly checkpoint]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 18:27:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:26:00 2009''

Revision as of 11:26, 17 February 2009

Image:2qyf.png

Template:STRUCTURE 2qyf

Crystal structure of the Mad2/p31(comet)/Mad2-binding peptide ternary complex

Template:ABSTRACT PUBMED 18022368

About this Structure

2QYF is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yang M, Li B, Tomchick DR, Machius M, Rizo J, Yu H, Luo X. p31comet blocks Mad2 activation through structural mimicry. Cell. 2007 Nov 16;131(4):744-55. PMID:18022368 doi:10.1016/j.cell.2007.08.048
  • Luo X, Tang Z, Xia G, Wassmann K, Matsumoto T, Rizo J, Yu H. The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat Struct Mol Biol. 2004 Apr;11(4):338-45. Epub 2004 Mar 14. PMID:15024386 doi:10.1038/nsmb748
  • Luo X, Tang Z, Rizo J, Yu H. The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol Cell. 2002 Jan;9(1):59-71. PMID:11804586
  • Luo X, Fang G, Coldiron M, Lin Y, Yu H, Kirschner MW, Wagner G. Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat Struct Biol. 2000 Mar;7(3):224-9. PMID:10700282 doi:10.1038/73338

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