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2hho

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==About this Structure==
==About this Structure==
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2HHO is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HHO OCA].
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2HHO is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HHO OCA].
==Reference==
==Reference==
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Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain., Hua QX, Nakagawa S, Hu SQ, Jia W, Wang S, Weiss MA, J Biol Chem. 2006 Aug 25;281(34):24900-9. Epub 2006 Jun 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16762918 16762918]
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<ref group="xtra">PMID:16762918</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Hu, S Q.]]
[[Category: Hu, S Q.]]
[[Category: Hua, Q X.]]
[[Category: Hua, Q X.]]
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[[Category: Mutant]]
[[Category: Mutant]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:57:14 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:20:08 2009''

Revision as of 13:20, 17 February 2009

Image:2hho.png

Template:STRUCTURE 2hho

Contents

NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures

Template:ABSTRACT PUBMED 16762918

Disease

Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[176730], Hyperproinsulinemia, familial OMIM:[176730], MODY, one form OMIM:[176730]

About this Structure

2HHO is a 2 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Hua QX, Nakagawa S, Hu SQ, Jia W, Wang S, Weiss MA. Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain. J Biol Chem. 2006 Aug 25;281(34):24900-9. Epub 2006 Jun 8. PMID:16762918 doi:http://dx.doi.org/10.1074/jbc.M602691200

Page seeded by OCA on Tue Feb 17 15:20:08 2009

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