2iko
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 2IKO is a | + | 2IKO is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IKO OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:17113558</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
- | [[Category: Single protein]] | ||
[[Category: Mochalkin, I.]] | [[Category: Mochalkin, I.]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
Line 35: | Line 34: | ||
[[Category: Renin]] | [[Category: Renin]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:54:58 2009'' |
Revision as of 13:54, 17 February 2009
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2iko, resolution 1.90Å () | |||||||||
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Ligands: | |||||||||
Gene: | REN (Homo sapiens) | ||||||||
Activity: | Renin, with EC number 3.4.23.15 | ||||||||
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Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
Coordinates: | save as pdb, mmCIF, xml |
Contents |
Crystal Structure of Human Renin Complexed with Inhibitor
Template:ABSTRACT PUBMED 17113558
Disease
Known disease associated with this structure: Renal tubular dysgenesis OMIM:[179820], Hyperproreninemia OMIM:[179820]
About this Structure
2IKO is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sarver RW, Peevers J, Cody WL, Ciske FL, Dyer J, Emerson SD, Hagadorn JC, Holsworth DD, Jalaie M, Kaufman M, Mastronardi M, McConnell P, Powell NA, Quin J 3rd, Van Huis CA, Zhang E, Mochalkin I. Binding thermodynamics of substituted diaminopyrimidine renin inhibitors. Anal Biochem. 2007 Jan 1;360(1):30-40. Epub 2006 Oct 30. PMID:17113558 doi:http://dx.doi.org/10.1016/j.ab.2006.10.017
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