1z3n
From Proteopedia
(Difference between revisions)
| Line 20: | Line 20: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1Z3N is a | + | 1Z3N is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3N OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:15857120</ref><references group="xtra"/> | |
[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Dicioccio, A T.]] | [[Category: Dicioccio, A T.]] | ||
[[Category: Geraci, L S.]] | [[Category: Geraci, L S.]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:03:20 2009'' |
Revision as of 14:03, 17 February 2009
Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom
Template:ABSTRACT PUBMED 15857120
About this Structure
1Z3N is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Van Zandt MC, Jones ML, Gunn DE, Geraci LS, Jones JH, Sawicki DR, Sredy J, Jacot JL, Dicioccio AT, Petrova T, Mitschler A, Podjarny AD. Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications. J Med Chem. 2005 May 5;48(9):3141-52. PMID:15857120 doi:10.1021/jm0492094
Page seeded by OCA on Tue Feb 17 16:03:20 2009
