1sc7
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 1SC7 is a | + | 1SC7 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SC7 OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:15801827</ref><references group="xtra"/> | |
[[Category: DNA topoisomerase]] | [[Category: DNA topoisomerase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Single protein]] | ||
[[Category: Burgin, A B.]] | [[Category: Burgin, A B.]] | ||
[[Category: Cushman, M.]] | [[Category: Cushman, M.]] | ||
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[[Category: Topoisomerase i]] | [[Category: Topoisomerase i]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:30:28 2009'' |
Revision as of 16:30, 17 February 2009
Contents |
Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex
Template:ABSTRACT PUBMED 15801827
Disease
Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[126420]
About this Structure
1SC7 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex. J Med Chem. 2005 Apr 7;48(7):2336-45. PMID:15801827 doi:10.1021/jm049146p
Page seeded by OCA on Tue Feb 17 18:30:28 2009
Categories: DNA topoisomerase | Homo sapiens | Burgin, A B. | Cushman, M. | Feese, M D. | Pommier, Y. | Staker, B L. | Stewart, L. | Zembower, D. | Dna | Drug | Idenoisoquinoline | Poison | Topoisomerase i