2d1j
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | 2D1J is a | + | 2D1J is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D1J OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:15911309</ref><ref group="xtra">PMID:15456260</ref><references group="xtra"/> | |
| - | + | ||
| - | + | ||
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Suzuki, M.]] | [[Category: Suzuki, M.]] | ||
[[Category: Blood coagulation factor]] | [[Category: Blood coagulation factor]] | ||
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[[Category: Serine protease]] | [[Category: Serine protease]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:21:04 2009'' |
Revision as of 18:21, 17 February 2009
Factor Xa in complex with the inhibitor 2-[[4-[(5-chloroindol-2-yl)sulfonyl]piperazin-1-yl] carbonyl]thieno[3,2-b]pyridine n-oxide
Template:ABSTRACT PUBMED 15911309
About this Structure
2D1J is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Komoriya S, Haginoya N, Kobayashi S, Nagata T, Mochizuki A, Suzuki M, Yoshino T, Horino H, Nagahara T, Suzuki M, Isobe Y, Furugoori T. Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites. Bioorg Med Chem. 2005 Jun 2;13(12):3927-54. PMID:15911309 doi:10.1016/j.bmc.2005.04.006
- Haginoya N, Kobayashi S, Komoriya S, Yoshino T, Suzuki M, Shimada T, Watanabe K, Hirokawa Y, Furugori T, Nagahara T. Synthesis and conformational analysis of a non-amidine factor Xa inhibitor that incorporates 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine as S4 binding element. J Med Chem. 2004 Oct 7;47(21):5167-82. PMID:15456260 doi:10.1021/jm049884d
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